Epitope Mapping Services for Antibody and Vaccine Research
At JPT Peptide Technologies, we offer advanced epitope mapping services to support antibody characterization, vaccine development, and immunological research. Our expertise in peptide synthesis, manufacturing PepStarTM peptide microarrays and screening enables precise identification of antigenic determinants, helping researchers optimize their targets with confidence.
JPT’s Comprehensive Epitope Mapping Services
Our tailored solutions support a wide range of applications, including antibody response profiling, biomarker discovery and serological test development. Our assay platforms are compatible with antibodies, serum, whole blood and other biological fluids. Our Epitope mapping service is based on our high-content or multiwell PepStarTM peptide microarrays and peptide ELISA.
- Linear and Conformational Epitope Mapping: Identifying key binding sites for monoclonal and polyclonal antibodies.
- Overlapping Peptide Scanning: Systematic mapping using high-throughput peptide microarrays for fine epitope resolution.
- Antibody Epitope Discovery: Peptides designed to identify immunodominant regions for vaccine development.
- Post-Translational Modification Mapping: Detection of modifications such as phosphorylation and glycosylation or cyclic peptides affecting immune recognition.
How does our Epitope Mapping Service work?
Send us a short description of your project and we will:
- Provide suggestions on array platform and controls to be used
- Provide a quotation for all-in-one services
- Perform synthesis of peptides and generation of PepStarTM peptide microarrays
- Incubate peptide microarrays with your sample
- Evaluate and interpret data • Assign signals to corresponding peptide sequences
- Quantify signals
- Provide a comprehensive and confidential report
- Provide a functional characterization of mapped epitopes
- Suggest follow-up experiments
Specifications of JPT’s Epitope Mapping Service
| Microarray Content | Single to multiple antigens translated into overlapping peptides |
| Peptide Length | 15 amino acids by default (adjustable) |
| Peptide Overlap | 11 amino acids by default (adjustable) |
| Data Input | Simply provide the protein sequence or UniProt ID |
| Analysis | We fully evaluate and interpret the data:
|
| Number of Peptides | Up to 3 x 6912 peptides |
| Peptide Purity | No truncated sequences |
| Peptide Replicates | Tripple spots by default (adjustable) |
| Sample Material | Approx. 1ng antibody per incubation (the exact amount depends on the sample) |
Why Choose JPT for Epitope Mapping?
- Expertise in Peptide-Based Immunology: Decades of experience in peptide synthesis, peptide microarrays and immunological applications.
- High-Throughput Screening: Scalable peptide microarray and library-based approaches for rapid discovery with up to 6900 peptides simultaneously.
- Customizable Array Design: Tailored mapping strategies to fit your specific research needs.
- Reliable & Reproducible Data: High-quality synthesis and screening ensuring accurate results.
- High Resolution: Allows identification of epitopes at the amino acid level.
- Cost-Effectiveness: Using PepStarTM peptide microarrays allows for low cost peptide screening.
Get in Touch
Looking to map critical epitopes for antibody or vaccine development? Contact us today to discuss your project and receive expert guidance.