SP-Ab-07_0.1

Beta-Amyloid (1-42) HFIP treated

US$189.00

Limited stock

Description

About Beta-Amyloid (1-42) HFIP treated

The Beta-Amyloid (1-42) peptide plays a crucial role in Alzheimer's disease research, making it an essential tool for scientists and researchers. This specific sequence corresponds to the most widely studied form of amyloid beta, known for its involvement in the formation of amyloid plaques in the brain, a hallmark of Alzheimer's disease.

Synthetic peptide derived from the N-terminal region of human Amyloid beta A4 protein (Swiss-Prot ID: P05067). HFIP treatment is performed to disrupt beta-sheets and other unwanted secondary structures.

Beta-Amyloid (1-42) HFIP treated - Specifications

Amino Acid Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Protein Name: Amyloid beta (A4) (alternative names: Abeta, Beta amyloid, APP)
Purity: >95% (HPLC-MS)
Delivery Format: Freeze-dried in plastic vial
Application(s):
Condition(s)/Topic(s): Alzheimer's disease
Standard Delivery Time: 2-5 days

Applications of Beta-Amyloid (1-42) in Alzheimer's Research

The Beta-Amyloid (1-42) peptide is widely used in studies related to:

  • Alzheimer's Disease Pathogenesis: Understanding the aggregation of amyloid plaques in neural tissues.
  • Drug Development: Screening and testing potential therapeutic agents that target amyloid beta aggregation.
  • Biomarker Discovery: Identifying early-stage biomarkers for Alzheimer's diagnosis.

Customization for Your Research Needs

At JPT Peptide Technologies, we understand that every research project has unique requirements. We offer tailored peptide synthesis services to match your specific needs, whether it’s beta amyloid 1-42, amyloid beta 1-42, or other variants of amyloid beta peptides. Choose your preferred sequence, amount, and purity, and our expert team will guide you through the process to ensure optimal results.

Why Choose JPT Peptide Technologies?

With over 20 years of experience in peptide synthesis, JPT is your trusted partner for high-quality, customized peptides. Our advanced facilities in Berlin, Germany, enable us to deliver tens of thousands of peptides each month, with a commitment to excellence and precision. Our Beta-Amyloid (1-42) peptides are no exception, offering researchers a reliable and consistent product for their Alzheimer's research.

Explore More Peptide Tools for Alzheimer's Research

Visit our webpage to explore a wide range of peptide tools designed specifically for Alzheimer's disease research. Whether you need other Abeta peptides, custom modifications, or detailed consultation, we are here to assist you every step of the way.

Visit our webpage for more Peptide Tools to Study Alzheimer's Disease

Are you interested in your other Abeta Peptides? Choose your sequence, amount and purity. We will assist you along the way. Custom Peptide Synthesis.

Learn More About JPT's Single Catalog Peptides

JPT's Single Catalog Peptides
JPT Peptide Technologies has substantial, long-standing expertise in providing peptides, peptidomimetics, and proteins to the global scientific community. Our highly skilled and committed scientific staff ensures that the most appropriate methods and techniques are selected for every synthesis project. All of JPT's catalog peptides are provided with HPLC-MS analyses to confirm the identity and demonstrate the high quality of our peptides.

Benefits of JPT's Single Catalog Peptides
- Synthesis protocols designed to avoid toxic contaminants and side products
- Provision of freeze dried aliquots for enhanced stability
- Proven track record for applications in clinical studies

References

References for Beta-Amyloid (1-42) HFIP treated

References:
Read References with Amyloid Beta A4 Peptides (abeta, aß)

Application Note
Synthetic Amyloid Beta Peptides Aid Alzheimer Investigation
Broersen et al., Application Note (2013) (full text)

Testimonial
Our group focuses on the in vitro study of risk factors in Alzheimer’s disease and, as we experienced that the in-house expression and production of the amyloid beta peptide is notoriously difficult, we are continuously dependent on a high quality supply of a large variety of these peptides from commercial source. We started our collaboration with JPT with their request to test a range of their peptides for the ability to produce toxic oligomers and fibrillar networks and were impressed by the rapid supply of a very wide range of high purity peptides with excellent fibril forming properties and toxicity profiles. JPT has shown real valuable know-how and experience in the field of peptide synthesis by their ability to generate high quality preparations of amyloid beta peptide variants which are known for their difficulty to handle.”
Kerensa Broersen, Assistant Prof., Nanobiophysics Group, University of Twente, Enschede, The Netherlands

Documentation

Documentation for Beta-Amyloid (1-42) HFIP treated

Properties

Properties of Beta-Amyloid (1-42) HFIP treated

Properties Values
Category: Abeta Peptides
Condition / Topic: Alzheimer's disease
Layout: Freeze-dried in plastic vial
Organism: Human
Protein Name: Amyloid beta (A4) protein
Purity: >95% (HPLC-MS)
Quantification: Yes

Further Information to Beta-Amyloid (1-42) HFIP treated

Information Values
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Specifications: Synthetic Beta-Amyloid peptide (1-42)
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