SP-Ab-07_0.1

Beta-Amyloid 1-42 HFIP treated

US$189.00

Currently out of stock, available again soon

Description

About Beta-Amyloid 1-42 HFIP treated

Beta amyloid 1-42 is a synthetic peptide widely used in Alzheimer's disease research due to its critical role in plaque formation in the brain. This form, treated with hexafluoroisopropanol (HFIP), ensures disruption of beta-sheets and reduces unwanted secondary structures, making it ideal for consistent experimental outcomes.

CAS: 107761-42-2
Synonyms: abeta 1 42, amyloid beta peptide 1-42, amyloid 1 42, amyloid 1-4

Synthetic peptide derived from the N-terminal region of human Amyloid beta A4 protein (Swiss-Prot ID: P05067). HFIP treatment is performed to disrupt beta-sheets and other unwanted secondary structures.

Beta-Amyloid 1-42 HFIP treated - Specifications

Peptide Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Protein Name: Amyloid beta (A4) (alternative names: Abeta, Beta amyloid, APP)
  • Purity: >95% (HPLC-MS)
  • Delivery Format: Freeze-dried in plastic vial
  • Application(s):
  • Condition(s)/Topic(s): Alzheimer's disease
  • Standard Delivery Time: approx. 3 weeks

Applications in Alzheimer Disease Research

Beta amyloid 1-42 is a crucial component in:
  • Understanding Alzheimer Pathogenesis: Understanding the aggregation of amyloid plaques in neural tissues.
  • Drug Discovery: Screening and testing potential therapeutic agents that target amyloid beta aggregation.
  • Biomarker Development: Identifying early-stage biomarkers for Alzheimer's diagnosis.
Its HFIP-treated form provides better reproducibility and structural consistency, making it a preferred choice for in vitro and in vivo studies.

Customization for Your Research Needs

At JPT Peptide Technologies, we understand that every research project has unique requirements. We offer tailored peptide synthesis services to match your specific needs, whether its beta amyloid 1-42, amyloid beta 1-42, or other variants of amyloid beta peptides. Choose your preferred sequence, amount, and purity, and our expert team will guide you through the process to ensure optimal results.

Why Choose JPT Peptide Technologies?

With over two decades of peptide synthesis expertise, JPT stands out for quality and precision. Our beta amyloid 1-42 peptides are produced under stringent quality standards at our ISO-certified facility in Berlin.


What Sets Us Apart:
  • Custom synthesis with guaranteed purity and sequence verification
  • High-throughput production capacity
  • Trusted partner in clinical and preclinical research
  • All peptides provided with HPLC-MS analysis
  • Explore More Peptide Tools for Alzheimer's Research

    Visit our webpage to explore a wide range of peptide tools designed specifically for Alzheimer's disease research. Whether you need other Abeta peptides, custom modifications, or detailed consultation, we are here to assist you every step of the way.

    Visit our webpage for more Peptide Tools to Study Alzheimer's Disease

    Are you interested in your other Abeta Peptides? Choose your sequence, amount and purity. We will assist you along the way. Custom Peptide Synthesis.

    References

    References for Beta-Amyloid 1-42 HFIP treated

    References:
    Read References with Amyloid Beta A4 Peptides (abeta, aß)

    Application Note
    Synthetic Amyloid Beta Peptides Aid Alzheimer Investigation
    Broersen et al., Application Note (2013) (full text)

    Testimonial
    Our group focuses on the in vitro study of risk factors in Alzheimer’s disease and, as we experienced that the in-house expression and production of the amyloid beta peptide is notoriously difficult, we are continuously dependent on a high quality supply of a large variety of these peptides from commercial source. We started our collaboration with JPT with their request to test a range of their peptides for the ability to produce toxic oligomers and fibrillar networks and were impressed by the rapid supply of a very wide range of high purity peptides with excellent fibril forming properties and toxicity profiles. JPT has shown real valuable know-how and experience in the field of peptide synthesis by their ability to generate high quality preparations of amyloid beta peptide variants which are known for their difficulty to handle.”
    Kerensa Broersen, Assistant Prof., Nanobiophysics Group, University of Twente, Enschede, The Netherlands

    Documentation

    Documentation for Beta-Amyloid 1-42 HFIP treated

    Properties

    Properties of Beta-Amyloid 1-42 HFIP treated

    Properties Values
    Category: Abeta Peptides
    Condition / Topic: Alzheimer's disease
    Layout: Freeze-dried in plastic vial
    Organism: Human
    Protein Name: Amyloid beta (A4) protein
    Purity: >95% (HPLC-MS)
    Quantification: No, Yes

    Further Information to Beta-Amyloid 1-42 HFIP treated

    Information Values
    Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
    Specifications: Synthetic Beta-Amyloid peptide (1-42)
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