Antigen Peptide Mouse MOG - H2-IAb (MEVGWYRSPFSRVVHLYRNGK) - AA 35 - 55 (= AA 63 - 83 including the signal sequence) for stimulation of antigen-specific T cells in T cell assays such as ELISPOT, ICS, cytotoxity or proliferation assays.
Antigen Peptide Mouse MOG - H2-IAb (MEVGWYRSPFSRVVHLYRNGK) - Specifications
Amount: 1 mg
Purity: Trial Grade: each peptide purified to > 90% (HPLC/MS)
Delivery Format: Freeze-dried in plastic vial
Application(s): Condition(s)/Topic(s): Standard Delivery Time: approx. 10 days
CAS: 163913-87-9
Peptide Name: Myelin Oligodendrocyte Glycoprotein Peptide 35-55, Mouse
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About Myelin Oligodendrocyte Glycoprotein Peptide 35-55; CAS: 163913-87-9
The Myelin Oligodendrocyte Glycoprotein Peptide 35-55 (MOG 25-55) is a well-characterized peptide derived from the extracellular domain of the MOG protein, specifically designed for use in murine models. This peptide sequence is widely utilized in research focused on autoimmune diseases, particularly experimental autoimmune encephalomyelitis (EAE), a commonly used animal model for multiple sclerosis (MS).
Applications for Myelin Oligodendrocyte Glycoprotein Peptide 35-55; CAS: 163913-87-9
Induction of EAE: MOG 35-55 peptide is commonly used to induce EAE in mice, providing a robust model to study the immunopathological mechanisms of MS (multiple sclerosis) and test potential therapeutic interventions.
Autoimmune Research: The peptide plays a crucial role in the study of autoimmune responses, allowing researchers to investigate the development and progression of demyelination and other MS-related processes.
Antigen-Specific T-Cell Stimulation: MOG 35-55 is used to study T-cell responses specific to myelin antigens, aiding in the understanding of how the immune system targets myelin in demyelinating diseases.
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