Phosphatase Substrate Identification
JPT provides highly comprehensive service to find substrates for your phosphatases using both phosphopeptides immobilized to glass surfaces (Phosphatase Peptide Microarrays) and soluble peptides in 384-well microtiter plates (Phosphatase Substrate Sets). Discuss your needs with our scientists and simply send us your phosphatase sample. JPT will perform all experiments and will deliver a data report including experimental details, fluorescence images or data from colorimetric readout and statistical analysis of results yielding consensus sequence motifs for your phosphatase substrates.
Benefits of Phosphatase Substrate Identification
- Select from more than 10 000 human phosphopeptides available on peptide microarrays
- Receive information about your phosphatase substrates and consensus sequence within two weeks
- Get information about potential downstream targets of your phosphatase
- Identify phosphatase contaminations in your sample
- Minimal sample volume needed (200 µL assay volume per peptide microarray)
Related products and services
Phosphatase Substrate Sets
Compilation of phosphatase substrate peptides in ready-to-use microtiter plates
Phosphatase Peptide Microarrays
Compilation of phosphatase substrate peptides on ready-to-use PepStar peptide microarrays
Kinase Substrate Identification
Kinase substrate identification service using JPT's peptide collections and microarrays
Protease Substrate Identification
Protease substrate identification service using JPT's peptide collections and microarrays
Selected References for Phosphatase Substrate Identification:
Diverse Driving Forces Underlie the Invariant Occurrence of the T42A, E139D, I282V and T468M SHP2 Amino Acid Substitutions Causing Noonan and LEOPARD Syndromes
Martinelli et al., Human Molecular Genetics (2008)
A Conserved Phosphatase Cascade that Regulates Nuclear Membrane Biogenesis
Kim et al., PNAS (2007)
More references under JPT Publications/Literature
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