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PepStar™ Peptide Microarrays

JPT Peptide Technologies applies its unique PepStar™ peptide microarray platform to generate customized peptide microarrays on glass slides for biomarker discovery, immuno monitoring and detection and validation of protein interactions. In addition, PepStar™ technology also enables characterization of enzyme target families such as kinases, phosphatases and proteases as well as methyl, glycosyl, acetyl transferases and lysine deacetylases.
Peptides are immobilized on glass slides via a flexible linker. Chemoselective coupling generates microarrays of directed and covalently attached peptides. Multiple identical copies of peptide microarrays can be prepared at unmatched prices and turnaround times. Incubation can be performed manually or automated and read-out is performed via fluorescence. This results in low backgrounds and high sensitivity.

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Applications for PepStar™ Peptide Microarrays:

  • Mapping of immunodominant regions in antigens
  • Identification of substrates for orphan enzymes
  • Optimization of known enzyme substrates
  • Elucidation of signal transduction pathways
  • Reliable detection of contaminating enzyme activities

Benefits of PepStar™ Peptide Microarrays:

  • Get hundreds of identical microarray copies from one peptide synthesis
  • Peptides are free of truncated sequences
  • Small amounts of your precious samples are needed for incubation
  • Low background on glass surface
  • Read-out via fluorescence
  • Save time for HTS assay setup
  • Screen thousands of potential peptide substrates economically
  • Learn more about the biology of your enzyme

Testimonials for PepStar™ Peptide Microarrays

"The RV 144 HIV trial is considered as one of first successful HIV vaccine trials. It has become clear that the V2 loop of gp120 is an important site for immunogenicity and protection from HIV infection. The use of JPT's PepStar™ microarray technology has been very useful for the correlation of the clincial outcome with humoral immune responses. As have the cyclic peptides been from JPT to validate these findings!"
Jeff Currier, PhD, Walter Reed Army Institute, Rockville, Maryland, USA

"Over the past five years my research team has been active in the development of species-specific peptide arrays. Our ability to advance this technology into new research areas has been dependent on working with the highest quality of arrays. In this regard, JPT’s commitment to excellence has been a critical foundation for the success of our research program. I have been consistently impressed with their customer service, technical expertise and professionalism. When it comes to peptide work there are no other options for our group…JPT is the best."
Scott Napper, PhD, Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Canada

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