Tailored PepStar™ Peptide Microarrays

JPT Peptide Technologies is the market leader for customized peptide microarrays on glass slides.  JPT's PepStar™ peptide microarrays (or simply peptide arrays) are efficient tools for seromarker discovery, immunomonitoring and for screening, mapping and validation of protein interactions. In addition, our PepStar™ microarray technology also enables enzyme profiling of methyl, glycosyl, acetyl transferases and lysine deacetylases, kinases, phosphatases and proteases.
PepStar™ microarray peptides are immobilized onto glass slides via a flexible linker. By chemoselective immobilization and a special synthesis technique, the peptides become purified during the immobilization process. From one peptide synthesis batch we can prepare multiple identical copies of each peptide microarray at unmatched pricing and turnaround time. Application protocols for both, manual and automated incubation with fluorescence read-out are delivered with all our peptide microarrays.

Applications for PepStar™ Peptide Microarrays:

  • Antibody epitope mapping
  • Identification & optimization of enzyme substrates
  • Screening for protein-protein interactions
  • Detection of contaminating enzymes in preparations

    Application Notes:
    Download our Application Note on PepStar™ Peptide Microarrays:
    "Antibody Signatures Defined by High-Content Peptide Microarray Analyses"
    by Schutkowski et al
    Download our Application Note on our modular seromarker profiling service:

    "A Modular Approach for Epitope Discovery and High-Resolution Profiling of Humoral Immune Responses"
    by N. Pawlowski et al

Benefits of PepStar™ Peptide Microarrays:

  • Cost-effective provision of large batches of identical microarray copies
  • Purified peptides are used
  • Consumes only small sample for incubation
  • Low background on glass surface
  • Read-out via fluorescence
  • Screen thousands of potential peptide substrates economically
  • Efficient high-throughput screening
  • Obtain Peptide ELISAs and peptide synthesis for validation

Testimonials for PepStar™ Peptide Microarrays:

"The RV 144 HIV trial is considered as one of first successful HIV vaccine trials. It has become clear that the V2 loop of gp120 is an important site for immunogenicity and protection from HIV infection. The use of JPT's PepStar™ microarray technology has been very useful for the correlation of the clincial outcome with humoral immune responses. As have the cyclic peptides been from JPT to validate these findings!"
Jeff Currier, PhD, Walter Reed Army Institute, Rockville, Maryland, USA

"Over the past five years my research team has been active in the development of species-specific peptide arrays. Our ability to advance this technology into new research areas has been dependent on working with the highest quality of arrays. In this regard, JPT’s commitment to excellence has been a critical foundation for the success of our research program.  I have been consistently impressed with their customer service, technical expertise and professionalism. When it comes to peptide synthesis there are no other options for our group…JPT is the best."
Scott Napper, PhD, Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Canada

More testimonials under JPT Testimonials

Selected References for PepStar™ Peptide Microarrays:

Abstracts available from PubMed: www.ncbi.nlm.nih.gov/pubmed

Peptide Microarrays Enable Rapid Mimotope Optimization for Pharmacokinetic Analysis of the Novel Therapeutic Antibody IMAB362
Schnatbaum et al., Biotechnol J. (2014) - PMID: 24497417
Peanut Oral Immunotherapy Modifies IgE and IgG4 Responses to Major Peanut Allergens
Vickery et al., J Allergy Clin Immunol. (2013) - PMID: 23199605
Plasma IgG to Linear Epitopes in the V2 and V3 Regions of HIV-1 gp120 Correlate with a Reduced Risk of Infection in the RV144 Vaccine Efficacy Trial
Gottardo et al., PLoS One. (2013) - PMID: 24086607
Nonreplicating Vaccines Can Protect African Green Monkeys From the Memphis 37 Strain of Respiratory Syncytial Virus

Eyles et al., The Journal of Infectious Disease (2013) - PMID: 23596321
Serum Autoantibodies to Myelin Peptides Distinguish Acute Disseminated Encephalomyelitis From relapsing– Remitting Multiple Sclerosis

Van Haren et al., Multiple Sclerosis Journal (2013) - PMID: 23612879
Neutralization of Porcine Endogenous Retrovirus by Antibodies Against the Membrane-Proximal External Region of the Transmembrane Envelope Protein

Wächter et al., Journal of General Virology (2013) - PMID: 23223617
Characterization of Humoral and Cellular Immune Responses Elicited by a Recombinant Adenovirus Serotype 26 HIV-1 Env Vaccine in Healthy Adults (IPCAVD 001)

Barouch et al., J. Immunol. (2013) - PMID: 23125443

More references under JPT Publications/Literature

Printer, PepStar™ Peptide Microarray and CD

Related products and services

Epitope Discovery Service
Take advantage of our comprehensive Full Service (incl. incubation, analyses and detailed report)

Three-Step Seromarker Profiling Service

Comprehensive and modular seromarker discovery workflow ranging from high throughput screening and parallel verification of peptide hits for hundreds of samples to validation of results by robust peptide ELISA

RepliTope™ Catalog Microarrays
Peptide chips for mapping immunodominant regions in antigens
Phosphorylation Site Detector and Kinase Peptide Microarrays
Compilation of kinase substrate peptides on ready-to-use PepStar peptide microarrays
Peptide Microarray Assay Service
Profiling service using high content PepStar peptide microarrays
Phosphatase Peptide Microarrays
Compilation of phosphatase substrate peptides on ready-to-use PepStar peptide microarrays

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PepStar™  Peptide Microarrays

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RepliTope™ Peptide Microarrays

News on PepStar™

NEW Application Note on Peptide Array based Seroprofiling in Multiple Sclerosis
Read the Application Note
Learn more about our Modular Seromarker Profiling Service

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Contact us!

Please feel free to call or send us an email to peptide@jpt.com
+1 978 631 4225 (US/Canada only)

JPT's Quality Assurance

All production is performed in JPT's head offices in Berlin, Germany according to ISO 9001:2008 standards