PepMix™ Peptide Pools

The use of mixtures of pooled overlapping peptides (e.g. for a certain virus or tumor antigens such as CMV pp65 or erbB2) or mixed antigenic peptides (e.g. CEF Pools with antigens from CMV, EBV and Influenza) is extremely efficient for immunostimulation of T-cells.  JPT Peptide Technologies offers a huge and still growing number of cost-effective and ready-to-use PepMix™ Peptide Pools and PepMix™ Peptide Pool Collections. Alternatively, we can prepare your customized peptide pool fast and economically according to your specific needs and even provide the respective individual peptides.

Control Peptide Pools for T-cell Assays

CEF Pool (extended)
Positive Control Pool of 32 peptides peptides selected from defined HLA class I-restricted T-cell epitopes for T cell assays (e.g. ELISPOT)
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CEF Pool (standard) (120nmol)
Positive Control Pool of 23 peptides peptides selected from defined HLA class I-restricted T-cell epitopes for T cell assays (antigen specific T-cell stimulation)
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CEF Pool (standard) (15nmol)
Positive Control Pool of 23 peptides peptides selected from defined HLA class I-restricted T-cell epitopes for T cell assays (e.g. ELISPOT)
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CEFT MHCII Pool
Pool of 14 peptides peptides selected from defined HLA class II-restricted T-cell epitopes for T cell assays (e.g. antigen specific T-cell stimulation)
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CEFT Pool
Positive Control Pool of 27 peptides peptides selected from defined HLA class I and II-restricted T-cell epitopes for T cell assays (e.g. ELISPOT)
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EF Pool
Positive Control Pool of 20 peptides peptides selected from defined HLA class I-restricted T-cell epitopes for T cell assays (e.g. ELISPOT)
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Negative Control Pool PepMix™ HIV-1 (Con B gag motif)
Negative Control Pool of 123 peptides selected from Con B gag motifs of Human immunodeficiency virus strains
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PepMix™ Human (Actin)
Negative Control Pool of 120 peptides derived from a peptide scan through Actin, alpha skeletal muscle of Homo sapiens (Human) for T cell assays
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PepMix™ Human (HLA classI Ig-like C1 type domain)
Negative Control Pool of 19 peptides derived from a peptide scan through HLA class I histocompatibility antigen, A-36 alpha chain of Homo sapiens
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PepMix™ Human (MOG)
Negative Control Pool of 29 peptides derived from a peptide scan through Myelin-oligodendrocyte glycoprotein (MOG) of Homo sapiens (Human)
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Positive Control Pool PepMix™ HCMVA (IE-1)
Positive Control Pool of 120 peptides derived from a peptide scan through 55 kDa immediate-early protein 1 (IE-1) of Human cytomegalovirus (HHV-5)
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Positive Control Pool PepMix™ HCMVA (IE-2)
Positive Control Pool of 143 peptides derived from a peptide scan through 45 kDa immediate-early protein 2 (IE-2) of Human cytomegalovirus (HHV-5).
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Positive Control Pool PepMix™ HCMVA (pp65)
Positive Control Pool of 138 peptides derived from a peptide scan through 65 kDa phosphoprotein (pp65) of Human cytomegalovirus (HHV-5)
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Peptide Pools for Infectious Diseases Antigens

PepMix™ AAV6 (Capsid protein VP1)
Pool of 182 overlapping peptides from Capsid protein VP1 of Adeno-associated virus 6 for T cell assays (antigen specific T-cell stimulation)
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PepMix™ BKV (capsid protein VP1)
Pool of 88 peptides derived from a peptide scan through Major capsid protein VP1 of BK polyomavirus for T cell assays (e.g. ELISPOT)
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PepMix™ BKV (capsid protein VP2)
Pool of 85 peptides derived from a peptide scan through Minor capsid protein VP2 of BK polyomavirus for T cell assays (e.g. ELISPOT)
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PepMix™ BKV (capsid protein VP2, isoform VP3)
Pool of 56 peptides derived from a peptide scan through Minor capsid protein VP2, isoform VP3 of BK polyomavirus for T cell assays
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PepMix™ BKV (large T antigen)
Pool of 170 peptides derived from a peptide scan through Large T antigen of BK polyomavirus for T cell assays (antigen specific T-cell stimulation)
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PepMix™ BKV (small T antigen)
Pool of 41 peptides derived from a peptide scan through Small t antigen of BK polyomavirus for T cell assays (e.g. antigen specific T-cell stimulation)
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PepMix™ Candida (MP65)
Pool of 92 peptides derived from a peptide scan through Mannoprotein MP65 of Candida albicans (Yeast) for T cell assays (e.g. ELISPOT)
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PepMix™ Collection EBV
Collection of 13 peptide pools through 13 immunodominant antigens of Epstein-Barr virus (EBV)
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PepMix™ Collection HCMV
Collection of 19 peptide pools derived from scans through 19 immuonodominant antigens of Human cytomegalovirus (HHV-5)
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PepMix™ EBV (BARF1)
Pool of 53 overlapping peptides from Secreted protein BARF1 (p53) of Epstein-Barr virus (EBV) for T cell assays (e.g. ELISPOT)
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PepMix™ EBV (BMLF1)
Pool of 117 peptides derived from a peptide scan through mRNA export factor EB2 (BMLF1) of Epstein-Barr virus (HHV4) for T cell assays
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PepMix™ EBV (BMRF1)
Pool of 99 peptides derived from a peptide scan through DNA polymerase processivity factor BMRF1 of Epstein-Barr virus (HHV4) for T cell assays
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PepMix™ EBV (BRLF1)
Pool of 149 peptides derived from a peptide scan through Transcription activator BRLF1 of Epstein-Barr virus (HHV4) for T cell assays
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PepMix™ EBV (BZLF1)
Pool of 59 peptides derived from a peptide scan through Trans-activator protein BZLF1 of Epstein-Barr virus (HHV4) for T cell assays
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PepMix™ EBV (EBNA-LP)
Pool of 124 peptides derived from a peptide scan through Epstein-Barr nuclear antigen leader protein (EBNA-LP) of Epstein-Barr virus (HHV4)
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PepMix™ EBV (EBNA1)
Pool of 158 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 1 (EBNA1) of Epstein-Barr virus (HHV4) for T cell assays
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PepMix™ EBV (EBNA2)
Pool of 119 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 2 (EBNA2) of Epstein-Barr virus (HHV4) for T cell assays
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PepMix™ EBV (EBNA3a)
Pool of 234 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 3 (EBNA3a) of Epstein-Barr virus (HHV4) for T cell assays
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PepMix™ EBV (EBNA3b)
Pool of 279 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 4 (EBNA3b) of Epstein-Barr virus (HHV4) for T cell assays
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PepMix™ EBV (EBNA3c)
Pool of 265 peptides derived from a peptide scan through Epstein-Barr nuclear antigen 6 (EBNA3c) of Epstein-Barr virus (HHV4) for T cell assays
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PepMix™ EBV (GP350/GP340)
Pool of 224 peptides derived from a peptide scan (15mers with 11 aa overlap) through Envelope glycoprotein GP350/GP340 of Epstein-Barr virus (HHV4)
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PepMix™ EBV (LMP1)
Pool of 94 peptides derived from a peptide scan through Latent membrane protein 1 (LMP1) of Epstein-Barr virus (HHV4) for T cell assays
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PepMix™ EBV (LMP2)
Pool of 122 peptides derived from a peptide scan through Latent membrane protein 2 (LMP2) of Epstein-Barr virus (HHV4) for T cell assays
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PepMix™ HAdV-3 (hexon protein)
Pool of 234 peptides derived from a peptide scan through Hexon protein of Human adenovirus 3 (HAdV-3) for T cell assays (e.g. ELISPOT)
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PepMix™ HAdV-5 (penton protein)
Pool of 140 peptides derived from a peptide scan through Penton protein of Human adenovirus 5 (HAdV-5) for T cell assays (e.g. ELISPOT)
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PepMix™ HBV (Capsid protein)
Pool of 44 peptides derived from a peptide scan through Capsid protein of Hepatitis B virus (HBV-A) for T cell assays (e.g. ELISPOT)
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PepMix™ HBV (Large envelope protein)
Pool of 98 peptides derived from a peptide scan through Large envelope protein of Hepatitis B virus (HBV-A) for T cell assays (e.g. ELISPOT)
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PepMix™ HCMVA (IE-1)
Positive Control Pool of 120 peptides derived from a peptide scan through 55 kDa immediate-early protein 1 (IE-1) of Human cytomegalovirus (HHV-5)
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PepMix™ HCMVA (IE-2)
Positive Control Pool of 143 peptides derived from a peptide scan through 45 kDa immediate-early protein 2 (IE-2) of Human cytomegalovirus (HHV-5).
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PepMix™ HCMVA (pp65)
Positive Control Pool of 138 peptides derived from a peptide scan through 65 kDa phosphoprotein (pp65) of Human cytomegalovirus (HHV-5)
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PepMix™ HCMVA (UL103)
Pool of 60 peptides derived from a peptide scan through Protein UL103 of Human cytomegalovirus (HHV-5) for T cell assays (e.g. ELISPOT)
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PepMix™ HCMVA (UL151)
Pool of 82 peptides derived from a peptide scan through Orf UL151 of Human cytomegalovirus (HHV-5) for T cell assays (e.g. ELISPOT)
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PepMix™ HCMVA (UL153)
Pool of 67 peptides derived from a peptide scan through Orf UL153 of Human cytomegalovirus (HHV-5) for T cell assays (e.g. ELISPOT)
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PepMix™ HCMVA (UL28)
Pool of 92 peptides derived from a peptide scan through Uncharacterized protein UL28 of Human cytomegalovirus (HHV-5) for T cell assays
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PepMix™ HCMVA (UL32)
Pool of 260 peptides derived from a peptide scan through Large structural phosphoprotein (UL32) of Human cytomegalovirus (HHV-5) for T cell assays
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PepMix™ HCMVA (UL36)
Pool of 117 peptides derived from a peptide scan through Uncharacterized protein UL36 of Human cytomegalovirus (HHV-5) for T cell assays
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PepMix™ HCMVA (UL40)
Pool of 53 peptides derived from a peptide scan through Uncharacterized protein UL40 of Human cytomegalovirus (HHV-5) for T cell assays
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PepMix™ HCMVA (UL48)_ 2 subpools
Pool of 2 x 281 peptides derived from a peptide scan through Deneddylase UL48 of Human cytomegalovirus (HHV-5) for T cell assays
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PepMix™ HCMVA (UL55)
Pool of 224 peptides derived from a peptide scan through Envelope glycoprotein B (UL55) of Human cytomegalovirus (HHV-5) for T cell assays
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PepMix™ HCMVA (UL82)
Pool of 137 peptides derived from a peptide scan through 71 kDa phosphoprotein (UL82) of Human cytomegalovirus (HHV-5) for T cell assays
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PepMix™ HCMVA (UL94)
Pool of 84 peptides derived from a peptide scan through Capsid-binding protein UL94 of Human cytomegalovirus (HHV-5) for T cell assays
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PepMix™ HCMVA (UL99)
Pool of 45 peptides derived from a peptide scan through Tegument protein UL99 of Human cytomegalovirus (HHV-5) for T cell assays (e.g. ELISPOT)
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PepMix™ HCMVA (US24)
Pool of 123 peptides derived from a peptide scan through Tegument protein US24 of Human cytomegalovirus (HHV-5) for T cell assays
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PepMix™ HCMVA (US29)
Pool of 113 peptides derived from a peptide scan through Uncharacterized protein HHRF4 (US29) of Human cytomegalovirus (HHV-5) for T cell assays
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PepMix™ HCMVA (US3)
Pool of 44 peptides derived from a peptide scan through Unique short US3 glycoprotein of Human cytomegalovirus (HHV-5) for T cell assays
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PepMix™ HCMVA (US32)
Pool of 43 peptides derived from a peptide scan through Uncharacterized protein HHRF7 (US32) of Human cytomegalovirus (HHV-5) for T cell assays
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PepMix™ HHV (U90)
Pool of 267 peptides derived from a peptide scan through Protein U90 of Human herpesvirus 6B for T cell assays (antigen specific T-cell stimulation)
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PepMix™ HHV6 (U54)
Pool of 112 peptides derived from a peptide scan through U54 of Human herpesvirus 6B for T cell assays (antigen specific T-cell stimulation)
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PepMix™ HIV (ENV) Ultra
Pool of 150 15meric peptides derived from Envelope glycoprotein gp160 designed to cover the high sequence diversity of the HI virus for T cell assays
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PepMix™ HIV (GAG) Ultra
Pool of 150 15meric peptides derived from Gag polyprotein designed to cover the high sequence diversity of the HIV virus for T cell assays (e.g. ELISPOT)
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PepMix™ HIV (NEF) Ultra
Pool of 150 15meric peptides derived from Nef protein designed to cover the high sequence diversity of the HI virus for T cell assays (e.g. ELISPOT)
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PepMix™ HIV (POL) Ultra
Pool of 150 15meric peptides derived from Pol Polyprotein designed to cover the high sequence diversity of the HI virus for T cell assays
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PepMix™ HIV-1 (Con B gag motif)
Negative Control Pool of 123 peptides selected from Con B gag motifs of Human immunodeficiency virus strains
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PepMix™ HPV 16 (Protein E6)
Pool of 37 peptides derived from a peptide scan through Protein E6 of Human papillomavirus type 16 for T cell assays (e.g. ELISPOT)
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PepMix™ HPV 16 (Protein E7)
Pool of 22 peptides derived from a peptide scan through Protein E7 of Human papillomavirus type 16 for T cell assays (e.g. ELISPOT)
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PepMix™ HPV 18 (Protein E6)
Pool of 37 peptides derived from a peptide scan through Protein E6 of Human papillomavirus type 18 for T cell assays (e.g. ELISPOT)
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PepMix™ HPV 18 (Protein E7)
Pool of 24 peptides derived from a peptide scan through Protein E7 of Human papillomavirus type 18 for T cell assays (e.g. ELISPOT)
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PepMix™ HPV16 (L1)
Pool of 124 overlapping peptides from Late major capsid protein L1 (L1) of Human papillomavirus type 16 (HPV) for T cell assays (e.g. ELISPOT)
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PepMix™ Influenza A (HA /Brisbane (H1N1))
Pool of 139 peptides derived from a peptide scan through Hemagglutinin of Influenza A virus (A/Brisbane/59/2007(H1N1)) for T cell assays
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PepMix™ Influenza A (HA /California (H1N1))
Pool of 139 peptides derived from a peptide scan through Hemagglutinin of Influenza A virus (A/California/07/2009(H1N1)) for T cell assays
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PepMix™ Influenza A (MP1 (H3N2))
Pool of 110 peptides derived from a peptide scan through Matrix protein 1 of Influenza A virus (strain A/Aichi/2/1968 H3N2) for T cell assays
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PepMix™ Influenza A (MP1 /California (H1N1))
Pool of 61 peptides derived from a peptide scan through Matrix protein 1 of Influenza A virus (A/California/08/2009(H1N1)) for T cell assays
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PepMix™ Influenza A (MP1/AnnArbor (H2N2)
Pool of 61 overlapping peptides from Matrix protein 1 (MP1) of Influenza A (H2N2) for T cell assays (e.g. ELISPOT)
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PepMix™ Influenza A (MP2 /California (H1N1))
Pool of 22 peptides derived from a peptide scan through Matrix protein 2 of Influenza A virus (A/California/08/2009(H1N1)) for T cell assays
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PepMix™ Influenza A (MP2/AnnArbor (H2N2)
Pool of 22 overlapping peptides from Matrix protein 2 (MP2) of Influenza A (H2N2) for T cell assays (e.g. ELISPOT)
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PepMix™ Influenza A (Neuraminidase/Turkey/1/2005(H5N1))
Pool of 110 peptides derived from a peptide scan through Neuraminidase of Influenza A for T cell assays (antigen specific T-cell stimulation)
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PepMix™ Influenza A (Neuroamidase /California (H1N1)
Pool of 115 peptides derived from a peptide scan through Neuraminidase of Influenza A virus (A/California/08/2009(H1N1)) for T cell assays
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PepMix™ Influenza A (NP (H3N2))
Pool of 122 peptides derived from a peptide scan through Nucleocapsid protein of Influenza A virus (strain A/Kitakyushu/159/1993 H3N2) for T cell assays
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PepMix™ Influenza A (NP/AnnArbor (H2N2)
Pool of 122 overlapping peptides from Nucleoprotein (NP) of Influenza A (H2N2) for T cell assays (e.g. ELISPOT)
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PepMix™ RSV (Fusion glycoprotein F0)
Pool of 141 peptides derived from a peptide scan through Fusion glycoprotein F0 of Human respiratory syncytial virus for T cell assays (e.g. ELISPOT)
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PepMix™ RSV (G glycoprotein)
Pool of 72 overlapping peptides from Major surface glycoprotein G (mG) of Human respiratory syncytial virus (RSV) for T cell assays
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PepMix™ RSV (nucleocapsid protein N)
Pool of 95 peptides derived from a peptide scan through Nucleoprotein N of Human respiratory syncytial virus for T cell assays (e.g. ELISPOT)
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PepMix™ VACV (Cell surface-binding protein, MVA105L)
Pool of 74 peptides derived from a peptide scan through Cell surface-binding protein (MVA105L) of Vaccinia virus (strain Ankara) for T cell assays
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PepMix™ VACV (Host range protein 2, MVA018L)
Pool of 35 peptides derived from a peptide scan through Host range protein 2 (MVA018L) of Vaccinia virus (strain Ankara) for T cell assay
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PepMix™ VACV (L3L)
Pool of 85 peptides derived from a peptide scan through Protein L3 of Vaccinia Virus (strain WR) for T cell assays (e.g. ELISPOT)
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PepMix™ VACV (Major core protein P4a, MVA 121L)_2 Subpools
Pool of 223 peptides (delivered in two subpools of 112 + 111 peptides) derived from a peptide scan through Major core protein P4a of Vaccinia virus
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PepMix™ VACV (MVA 074R)
Pool of 106 peptides derived from a peptide scan through Putative 49.8k protein (MVA 074R) of Vaccinia virus (strain Ankara) for T cell assays
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PepMix™ VACV (MVA093L)
Pool of 79 peptides derived from a peptide scan through IMV heparin binding surface protein (MVA093L) of Vaccinia virus (strain Ankara) for T cell assays
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PepMix™ VACV (MVA189R)
Pool of 45 peptides derived from a peptide scan through Putative 21.7k protein (MVA189R) of Vaccinia virus (strain Ankara) for T cell assays
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PepMix™ VZV (IE62)_2 subpools
Pool of 325 peptides (delivered in two subpools of 163 + 162 peptides) derived from a peptide scan through Transcriptional transactivator IE62 of Varicella-zoster virus (strain Oka vaccine)
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PepMix™ VZV (IE63)
Pool of 67 peptides derived from a peptide scan through Transcriptional transactivator IE63 of Varicella-zoster virus (strain Oka vaccine) for T cell assays
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PepMix™ Yellow fever (NS4B)
Pool of 60 peptides derived from a peptide scan through Yellow fever Non-structural protein 4B of Yellow fever virus for T cell assays
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Peptide Pools for Tumor Associated Antigens

PepMix™ Arabidopsis (WRKY47)
Pool of 120 peptides derived from a peptide scan through Probable WRKY transcription factor 47 of Arabidopsis thaliana (Mouse-ear cress)
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PepMix™ Human (CEA)
Pool of 173 peptides derived from a peptide scan through Carcinoembryonic antigen-related cell adhesion molecule 5 of Homo sapiens (Human)
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PepMix™ Human (Claudin-6)
Pool of 53 peptides derived from a peptide scan through Claudin-6 of Homo sapiens (Human) for T cell assays (antigen specific T-cell stimulation)
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PepMix™ Human (Cyclin-B1)
Pool of 106 peptides derived from a peptide scan through G2/mitotic-specific cyclin-B1 of Homo sapiens (Human) for T cell assays (e.g. ELISPOT)
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PepMix™ Human (ErbB2_ECD)
Pool of 161 peptides derived from a peptide scan through Receptor tyrosine-protein kinase erbB-2 (extracellular domain) of Homo sapiens
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PepMix™ Human (ErbB2_ICD)
Pool of 146 peptides derived from a peptide scan through Receptor tyrosine-protein kinase erbB-2 (intracellular domain) of Homo sapiens (Human)
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PepMix™ Human (Histone H1.2)
Pool of 51 peptides derived from a peptide scan through Histone H1.2 of Homo sapiens (Human) for T cell assays (antigen specific T-cell stimulation)
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PepMix™ Human (Histone H4)
Pool of 23 peptides derived from a peptide scan through Histone H4 of Homo sapiens (Human) for T cell assays (e.g. antigen specific T-cell stimulation)
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PepMix™ Human (MAGEA1)
Pool of 75 peptides derived from a peptide scan through Melanoma-associated antigen 1 (MAGEA1) of Homo sapiens (Human) for T cell assays
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PepMix™ Human (MAGEA3)
Pool of 76 peptides derived from a peptide scan through Melanoma-associated antigen 3 (MAGEA3) of Homo sapiens (Human) for T cell assays
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PepMix™ Human (MAGEA4)
Pool of 77 peptides derived from a peptide scan through Melanoma-associated antigen 4 (MAGEA4) of Homo sapiens (Human) for T cell assays
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PepMix™ Human (Mammaglobin A)
Pool of 21 peptides derived from a peptide scan through Mammaglobin-A of Homo sapiens (Human) for T cell assays (e.g. ELISPOT)
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PepMix™ Human (Melan-A/MART-1)
Pool of 27 peptides derived from a peptide scan through Melanoma antigen recognized by T-cells 1 (MART-1) of Homo sapiens for T cell assays
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PepMix™ Human (Melanocyte protein Pmel 17 gp100)
Pool of 163 peptides derived from a peptide scan through Melanocyte protein Pmel 17 (gp100) of Homo sapiens (Human) for T cell assays
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PepMix™ Human (Metalloreductase STEAP1)
Pool of 82 peptides derived from a peptide scan through Metalloreductase STEAP1 of Homo sapiens (Human) for T cell assays
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PepMix™ Human (Myc protein)
Pool of 107 peptides derived from a peptide scan through Myc proto-oncogene protein of Homo sapiens (Human) for T cell assays
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PepMix™ Human (NY-ESO-1)
Pool of 43 peptides derived from a peptide scan through Cancer/testis antigen 1 (NY-ESO-1) of Homo sapiens for T cell assays (e.g. ELISPOT)
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PepMix™ Human (P53)
Pool of 96 peptides derived from a peptide scan through Cellular tumor antigen p53 of Homo sapiens (Human) for T cell assays (e.g. ELISPOT)
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PepMix™ Human (PAP)
Pool of 94 overlapping peptides from Prostatic acid phosphatase (PAP) of Homo sapiens (human) for T cell assays (e.g. ELISPOT)
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PepMix™ Human (Prame/OIP4)
Pool of 125 peptides derived from a peptide scan through Melanoma antigen preferentially expressed in tumors (PRAME/OIP4) of Homo sapiens (Human)
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PepMix™ Human (Prostate-specific antigen PSA)
Pool of 63 peptides derived from a peptide scan through Prostate-specific antigen of Homo sapiens (Human) for T cell assays (e.g. ELISPOT)
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PepMix™ Human (SOX-2)
Pool of 77 peptides derived from a peptide scan through Transcription factor SOX-2 of Homo sapiens (Human) for T cell assays
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PepMix™ Human (SSX2)
Pool of 45 peptides derived from a peptide scan through Protein SSX2 of Homo sapiens (Human) for T cell assays (e.g. ELISPOT)
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PepMix™ Human (Stromelysin-3, MMP11)
Pool of 121 peptides derived from a peptide scan through Stromelysin-3 (MMP11) of Homo sapiens (Human) for T cell assays
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PepMix™ Human (Survivin)
Pool of 33 peptides derived from a peptide scan through Baculoviral IAP repeat-containing protein 5 (Survivin) of Human for T cell assays
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PepMix™ Human (TCRgamma alternate reading frame protein TARP)
Pool of 12 peptides derived from a peptide scan through TCRgamma alternate reading frame protein of Homo sapiens (Human) for T cell assays
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PepMix™ Human (Tyrosinase)
Pool of 117 peptides derived from a peptide scan through Tyrosinase of Homo sapiens (Human) for T cell assays (antigen specific T-cell stimulation)
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PepMix™ Human (Tyrosinase-related protein 2)
Pool of 127 peptides derived from a peptide scan through L-dopachrome tautomerase (Tyrosinase-related protein 2) of Homo sapiens (Human)
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PepMix™ Human (WT1/WT33)
Pool of 110 peptides derived from a peptide scan through Wilms tumor protein (WT33) of Homo sapiens (Human) for T cell assays (e.g. ELISPOT)
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PepMix™ Mouse (Survivin)
Pool of 33 peptides derived from a peptide scan through Baculoviral IAP repeat-containing protein 5 of Mus musculus for T cell assays (e.g. ELISPOT)
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PepMix™ Mouse (Tyrosinase)
Pool of 117 peptides derived from a peptide scan through Tyrosinase of Mus musculus (Mouse) for T cell assays (antigen specific T-cell stimulation)
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Tailored PepMixes™ & Matrix Peptide Pools

Custom PepMixes™ Peptide Pools

You need a specific antigen or specialized peptide pool layout?
We are happy to discuss your specifications and provide your tailored PepMixes™ or matrix pool. Our customer support team will assist with sequence and pool design. Subsequently, we will chemically synthesize, purify and analyze the peptides in compliance with the requirements of T-cell assays. All peptide synthesis steps are optimized to avoid contaminations and failure sequences which may lead to false positive T-cell responses or inhibition of T-cell responses.
Pooling and aliquotation will be performed using our validated protocol that ensures presence of all peptides in the respective pools. Our fully automated aliquotation service yields freeze dried pool aliquots which prevent deterioration of peptides as a major source for limited assay reproducibility.

Custom PepMix Production

Production of Customized PepMix Peptide Pools

Individual Peptides

In addition to tailored and off-the-shelf PepMix™ Peptide Pools, we are happy to provide the individual peptides to validate results or for further experiments.  As for the PepMix™ Peptide Pools, each individual peptide is quality controlled to ensure batch-to-batch reproducibility!
Our peptide synthesis, purification as well as aliquotation and pooling are controlled by our ISO certified quality management system.

Please inquire via email!

Applications for PepMix™ Peptide Pools

  • Antigen specific immunostimulation of T-lymphocytes
  • Monitoring of immune status during diseases or therapy
  • Assessment of vaccine efficacy
  • T-cell expansion
  • Cellular immune response profiling
  • Identification of the best antigen for individual patients (PepMix™ Collections)

    Application Notes:


    Download our Application Note on CMV PepMixes™:
    "Cytomegalovirus protein spanning PepMix™ peptide pools to discover changes in T cell immunity in the aging population"
    by F. Kern, Brighton and Sussex Medical School, UK

    Download our Application Note on PepMixes™ Peptide Pools for Clinical Applications:
    "T cell therapy for viral infections after hematopoietic stem cell transplant"
    by A. M. Leen, Baylor College of Medicine TX, USA

    Download our Application Note on Peptide library and pool qualification for clinical trials:
    "Qualification and use of peptide libraries for clinical trial immunomonitoring"
    by Josephine H Cox & Peter Hayes, The International AIDS Vaccine Initiative, London, GB

Benefits of PepMix™ Peptide Pools

Peptide pools are preferable to whole proteins for T cell stimulation because:

  • Equivalent or better stimulation of CD4 and CD8 cells
  • More reliable as control than phytohemagglutinin (PHA) and concanavalin A (ConA)
  • Improved responses in stored blood and PBM cells
  • High-batch-to-batch reproducibility
  • Reliable chemical and biochemical quality control and quality assurance are applicable for peptide synthesis and peptide pool generation
  • Prolonged shelf stability when stored freeze dried

    Testimonials for PepMix™ Peptide Pools


    "I have used JPT's peptide pools (PepMix™) for years now, with great satisfaction! First CMV derived peptides and now also EBV. So far we have published data in one publication and plan several more in the near future."

    Anna Karin Lidehaell (Uppsala University, Clin. Immunol., Uppsala, Sweden)

    "The main focus of my research group at the Charité in Berlin is the development of novel immunotherapeutic approaches against cancer and infectious diseases. For reliable monitoring of tumor and virus specific T-cell responses we have a permanent need for peptide synthesis and peptide pools that are produced in a regulated environment for application in a clinical environment. JPT has been a long term and dedicated partner in this regard which continuously works on improving it's peptide based services."
    Prof. Dr. Carmen Scheibenbogen, Charité Berlin, Germany

    More testimonials under JPT Testimonials

    Selected References for PepMix™ Peptide Pools:

    Abstracts available from PubMed: www.ncbi.nlm.nih.gov/pubmed

     

    Control Pools:
    Statistical Methods for the Assessment of EQAPOL Proficiency Testing: ELISpot, Luminex, and Flow Cytometry
    Rountree et al., J Immunol Methods (2014) - PMID: 24456626
    Polyfunctional T Cells Accumulate in Large Human Cytomegalovirus-Specific T Cell Responses
    Lachmann et al., J. Virol. (2012) - PMID: 22072753
    Generation of a Multipathogen-Specific T-cell Product for Adoptive Immunotherapy Based on Activation-Dependent Expression of CD154
    Khanna et al., Blood (2011) - PMID: 21642594
    AdCD40L Immunogene Therapy for Bladder Carcinoma—The First Phase I/IIa Trial
    Malmström et al., Clin. Cancer Res. (2010) - PMID: 20448220

    Infectious Diseases:
    Activity of Broad-Spectrum T Cells as Treatment for AdV, EBV, CMV, BKV, and HHV6 Infections After HSCT
    Papadopoulou et al., Sci Transl Med. (2014) - PMID: 24964991
    A Novel Cytomegalovirus-Induced Regulatory-Type T-Cell Subset Increases in Size During Older Life and Links Virus-Specific Immunity to Vascular Pathology

    Terrazzini et al., The Journal of Infectious Disease (2013) - PMID: 24203779
    Putting Polyphosphates to the Test: Evidence Against Platelet-Induced Activation of Factor XII
    Faxälv et al., Blood, (2013) - PMID: 23896408
    Characterization of the T-Cell–Mediated Immune Response Against the Aspergillus fumigatus Proteins Crf1 and Catalase 1 in Healthy Individuals
    Jolink et al., The Journal of Infectious Disease (2013) - PMID: 23698813
    Antibody Quality and Protection from Lethal Ebola Virus Challenge in Nonhuman Primates Immunized with Rabies Virus Based Bivalent Vaccine
    Blaney et al., PLOS Pathogens (2013) - PMID: 23737747
    Donor-Derived CMV-Specific T Cells Reduce The Requirement For CMV-Directed Pharmacotherapy After Allogeneic Stem Cell Transplantation
    Blyth et al., Blood. (2013) - PMID: 23435462
    An Adjuvanted Herpes Simplex Virus 2 Subunit Vaccine Elicits a T Cell Response in Mice and Is an Effective Therapeutic Vaccine in Guinea Pigs
    Skoberne et al., J. Virol. (2013) - PMID: 23365421
    Distinct Gene-expression Profiles Associated With the Susceptibility of Pathogen-Specific CD4 T Cells to HIV-1 Infection
    Hu et al., Blood. (2013) - PMID: 23258923
    T-cell Therapy for EBV-Associated Nasopharyngeal Carcinoma: Preparative Lymphodepleting Chemotherapy Does not Improve Clinical Results
    Secondino et al., Ann. Onc. (2012) - PMID: 21586688


    Tumor Associated Antigens:
    Cytotoxic T Lymphocytes Simultaneously Targeting Multiple Tumor-associated Antigens to Treat EBV Negative Lymphoma
    Gerdemann et al., Molecular Therapy (2011) - PMID: 21915103
    Improving T-cell Therapy for Relapsed EBV-Negative Hodgkin Lymphoma by Targeting Upregulated MAGE-A4
    Cruz et al., Clin. Cancer Res. (2011) - PMID: 21908573
    Prophylactic Transfer of BCR-ABL–, PR1-, and WT1-Reactive Donor T Cells after T cell–Depleted Allogeneic Hematopoietic Cell Transplantation in Patients with Chronic Myeloid Leukemia
    Bornhäuser et al., Blood. (2011) - PMID: 21540460

    More references under JPT Publications/Literature

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