Micro-Scale Peptides
JPT Peptide Technologies has the unique ability to produce complex peptide libraries made of up to 1 million single, individual peptides with rapid turnarounds at unmatched pricing.
Our patented SPOT technology allows for the synthesis of thousands of peptides on membrane supports. The resulting singular peptides are then transferred into microtiterplates and lyophilized. Over the years, JPT has produced more than 5 million individual peptides to customers worldwide.
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Applications:
- Screening for proteotypic peptides
- Validation and optimization of MRM assays
- Genome spanning peptide libraries
- Systematic biomarker screening
- Peptide microarray production
- T-cell epitope mapping
- Systematic optimization of peptide lead structures
- Generation of peptide pools for immune monitoring
- Screening assays for biological activity
- GPCR deorphanization
Product Specifications:
- Amounts of 50-250 nmole per peptide
- Peptide length: 6-20mers
- C-terminal acid or amide
- Non natural and isotopically labeled amino acids
- Ready-to-use peptides in 96/384-well plates
- Patented high-throughput SPOT-technology
- Full analysis (MALDI, LC-MS) available
Benefits:
- Highly parallel synthesis approach (30 000 peptides/week)
- Pricing from 7 €/$ per peptide
- Ready-to-use peptides in 96/384-well plates
- Turnaround: 2 weeks for 10 000 peptides
Selected References:
- An Unconventional IAP-Binding Motif Revealed by Target-Assisted Iterative Screening (TAIS) of the BIR3-cIAP1 Domain
Kurakin & Bredesen, J. Mol. Recognit. (2007) (abstract) - Related Prediction of Sequence-Dependent and Mutational Effects on the Aggregation of Peptides and Proteins
Fernandez-Escamilla et al., Nat. Biotechnol. (2004)(abstract) - Analysis of Antigen-Specific T-Cell Responses with Synthetic Peptides - What Kind of Peptide for Which Purpose?
Kiecker et al., Nat. Biotechnol. (2004) (abstract) - Systematic Identification of Tuberculosis T-Cell Epitopes with OHSU (link)
- JPT and Bayer Enter into Service Agreement on Complex Peptide Set Production (link)
More references under JPT Publications/Literature
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