Products

Peptrack™ Peptide Libraries


JPT Peptide Technologies is the leading provider of peptide libraries for T-cell assays and proteomic applications worldwide. Together with its partners in the vaccine industry, governmental and non-profit organizations, as well as universities JPT defined specific requirements for peptides to be used for T-cell assays in the various phases of vaccine development. These specifications were translated to a product line called PepTrack™ Peptide Libraries offering tailor made solutions for all peptide needs in vaccine development. Using its regulated environment (DIN EN ISO 9001:2008, GCLP), JPT produces more individual peptides on an annual basis than any other company worldwide.


Available PepTrack Options:

                  Fast Track                Most inexpensive source of small scale unpurified peptides for high-throughput
                                                   (proteome-wide) T-cell epitope/ biomarker discovery

                  Research Track        Milligram scale, unpurified peptides optimized for T-cell assays (reduction of false
                                                   positive T-cell responses, cross contamination and toxic contaminations) for T-cell
                                                   epitope mapping by ELISPOT, ICS, CFC etc. 

                  Discovery Track       Milligram scale peptides with guaranteed purity for T-cell assays in immune
                                                   monitoring and peptide pool generation

                  Trial Track                Milligram scale peptides with highest purity for T-cell assays in clinical trials

All PepTrack Levels are optimized towards performance in T-cell assays

Fast Track

Synthesized by JPT’s proprietary synthesis method Fast Track Peptide Libraries represent the most inexpensive source of peptides worldwide. The ability to produce tens-of-thousands of peptides within weeks offers T-cell epitope discovery, biological screening and identification of proteotypic peptides at proteome-wide levels.

Purity QA/QC Length Scale* Delivery Price/peptide
Unpurified - no purity guarantee! 5% LC-MS 7-15aa 50 - 250nmol 2 weeks from 7 $ / €
* additional QC available upon request
Delivery Format: 96-well plate format

Research Track

Research Track Peptide Libraries are designed for applications in T-cell assays requiring large numbers of fully analyzed peptides in quantities of 1-5mg. All peptides are fully analyzed for identity and purity by LC-MS (no MALDI-MS!). In addition, JPT’s peptide synthesis protocols are optimized to avoid contaminations and failure sequences which cause either false positive T-cell responses or toxic inhibition.

Purity QA/QC Length Scale* Delivery Price/peptide
Unpurified - no purity guarantee! LC-MS 7-15aa 1-5mg 2 weeks from 25 $ / €
Main product corresponds to target peptide LC-MS 7-15aa 1-5 mg 2 weeks please inquire
* for larger amounts please inquire
Delivery Format: 96-array tube format

Discovery Track

Discovery Track Peptide Libraries have defined purities for applications requiring similar and specified purities of all peptides (i.e. immune monitoring). Each peptide has a guaranteed minimum specification. All peptides will be QC’d by LC-MS (not MALDI-MS!). 

Purity QA/QC Length Scale* Delivery Price/peptide
 >70% LC-MS 7-15aa 1-5 mg 3 weeks from 45 $ / €
*for larger amounts please inquire
Delivery Format: 96-array tube format

Trial Track

Trial Track Peptide Libraries were designed to provide a reliable source of peptides and peptide pools for application as monitoring tools in clinical vaccination trials. All productions run in a regulated environment according to DIN EN ISO 9001:2008 & Good Clinical Laboratory Practices (GCLP) regulations. Synthesis protocols were optimized to reduce toxic contaminations as well as formation of deletion peptides and cross contaminants causing false positive T-cell responses. All peptides have guaranteed purities. 

Purity QA/QC Length Scale* Delivery Price/peptide
>80% LC-MS 7-15aa 1-5mg 2 weeks from 69 $ / €
>90% LC-MS 7-15aa 1-5mg 3 weeks please inquire
>95% LC-MS 7-15aa 1-5mg 4 weeks please inquire
>97% LC-MS 7-15aa 1-5mg 5 weeks please inquire
* full analytical coverage including amino acids analysis, capillary electrophoresis, peptide content determination, determination of residual solvents etc. is available upon request
** for larger amounts please inquire
Delivery Format: 96-array tube format

Benefits:

  • Selection of different peptide specifications tailored for cell based assay applications
  • Best pricing in industry starts at 7 $/€ per peptide
  • Whole production performed in a regulated European environment according to DIN EN ISO 9001:2008 & GCLP standards; audits welcome!
  • Synthesis protocols designed to avoid toxic contaminants and side products causing false positive T-cell responses
  • Special synthesis technology inhibits side products causing false positive T-cell responses
  • Provision of freeze dried aliquots for enhanced stability, validated pooling & vialing available
  • Proven track record for applications in clinical studies

 


Applications:

  • T-cell epitope discovery
  • Peptide vaccine development
  • T-cell epitope mapping and validation
  • Immune monitoring
  • Optimization and validation of T-cell assays
  • Vaccine efficacy testing
  • Cell therapy approaches
  • Biological screening
  • Identification of proteotypic peptides

Please inquire about additional services not listed here.

Testimonials

"I have been collaborating with JPT for several years. Their unique peptide library technologies and knowledge of specific peptide requirements for T-cell assays made them a valuable, long-term partner in our efforts to develop novel adoptive immunotherapy approaches to prevent and treat viral infections post-transplant as well as for the treatment of virus and non virus-associated malignancies. Furthermore, their reagents allow us to precisely monitor and track specific T cell populations post-infusion"
Ann Leen, PhD (Baylor College of Medicine, Center for Cell and Gene Therapy, Houston, TX, USA)


“We utilize JPT’s peptide libraries and pools for T-cell epitope mapping and immune monitoring applications such as ELISPOT and ICS, as well as CFC. The combination of synthesis economy, quick turnaround time and tailored specifications are key to our success. JPT’s scientific competence is invaluable for all institutions planning to employ peptides in immuno assays for research or clinical setups."
Johannes Hampl, PhD (Anza Therapeutics, Inc Concord, CA, USA)

More references under JPT Publications/Literature

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