Bio- & Cheminformatics
JPT has a long standing and focused expertise to escort biomedical screening and peptide lead optimization programs with its comprehensive bioinformatic and cheminformatic capabilities.
We offer this unique know-how and expertise as part of our high content peptide microarray and library services or in R&D collaborations focusing on peptide hit discovery and optimization.
Service Specifications
- Detailed discussion of your project and definition of a suitable strategy based on scientific feasibility and experience
- Receive project proposal on how our bio- and cheminformatic expertise can support your project
- Obtain detailed and comprehensive service reports
To obtain a quote, please contact our customer support: peptide@jpt.com
Benefits
- Long term track record on the discovery and development of peptides in drug discovery and diagnostic development
- State of the art prediction, data interpretation and data mining algorithms and software paired with chemical and biological know-how
- Expertise available as a fee-for-service or in collaborative partnerships
Applications
- Design of peptide content for high-density peptide microarrays and complex peptide libraries
- Design of peptide libraries based on biological pathways, literature data or complex database search strategies
- Generation of homology models and use of available structural information for peptide selection
- Optimization of hit and lead structures (affinity, physicochemical properties, ADME)
- Prediction and modeling of data
- Scaffold design for native-like presentation of peptides
- Interpretation, management and integration of data
Selected References
Stragies et al., J. of Medicinal Chemistry (2007) (abstract)
Hummel et al., Mol. BioSyst. (2006) (abstract)
More references under JPT Publications/Literature
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